This introduction course will address clinical research from a quantitative viewpoint. It will discuss risk, diagnosis, prognosis and treatment and the main options in studying clinical questions. The emphasis will be on validity of study design and interpretation of results. In particular, the observational study design and randomized clinical trial for efficacy research will be addressed. The course will have hands-on exercises on designing a study, interpretation of bias and taking account for confounding.
objectives
- Gain insght in clinical research from a quantitative viewpoint, with emphasis on validity of study design.
- Ability to apply major data-analytic and statistical techniques, such as the Kaplan-Meier actuarial method, the log-rank approach, logistic regression, and proportional hazards regression.